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    Expert tip

    If you need more than 65536 methods on your application you need to change your Gradle configuration to enable MultiDex and modify your manifest to reference MultiDex class.

Solutions on the web

via miui.com by Unknown author, 1 year ago
Failed to open dex files from /system/app/Calculator/Calculator.apk
via Stack Overflow by creck
, 1 year ago
Failed to open dex files from /data/app/custom.package.name-2/base.apk
via xda-developers.com by Unknown author, 1 year ago
No original dex files found for dex location /system/priv-app/SetupWizard/SetupWizard.apk
via GitHub by rom1v
, 1 year ago
No original dex files found for dex location /system/app/Exchange2/Exchange2.apk
via Stack Overflow by goncalveslucasv
, 4 months ago
No original dex files found for dex location /data/app/com.rnauth-2/base.apk
java.io.IOException: Failed to open dex files from /system/app/Calculator/Calculator.apk	at dalvik.system.DexFile.openDexFileNative(Native Method)	at dalvik.system.DexFile.openDexFile(DexFile.java:295)	at dalvik.system.DexFile.(DexFile.java:80)	at dalvik.system.DexFile.(DexFile.java:59)	at dalvik.system.DexPathList.loadDexFile(DexPathList.java:279)	at dalvik.system.DexPathList.makePathElements(DexPathList.java:248)	at dalvik.system.DexPathList.(DexPathList.java:120)	at dalvik.system.BaseDexClassLoader.(BaseDexClassLoader.java:48)	at dalvik.system.PathClassLoader.(PathClassLoader.java:65)	at android.app.ApplicationLoaders.getClassLoader(ApplicationLoaders.java:57)	at android.app.LoadedApk.getClassLoader(LoadedApk.java:376)	at de.robv.android.xposed.XposedBridge$1.beforeHookedMethod(XposedBridge.java:190)	at de.robv.android.xposed.XposedBridge.handleHookedMethod(XposedBridge.java:720)